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KMID : 0390220000110010115
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Journal of Clinical Otolaryngology, Head and Neck Surgery
2000 Volume.11 No. 1 p.115 ~ p.119
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A Case of Malignant External Otitis with Skull Base Extension
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Abstract
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Malignant external otitis is a potentially life-threatening infection of the external auditory canal and skull base.
typically seen in eldrely diabetic or immunocompromised patients. Pseudomonas aeruginosa is the bacteria most
commonly responsible for the infection. The disease process begins as an external otitis that may progress into
an osteomylitis of the skull base. Cranial nerve palsies may occur as the disease progresses, and in some cases,
sigmoid sinus thrombosis and menigitis have resulted in death. Treatment requires intensive long-term an-
tibiotic therapy with routine radiographic evaluations to monitor the disease process. Despite this, resistance to
antibiotic therapy can occur, resulting in recurrence of the disease that may be associated with a high in-cidence
of mortality. We have recently experienced one case of malignant external otitis with skull base extension in a
54-year-old male who was treated with open cavity mastoidectomy and long-term antibotic therapy, and report
this case with review of literatures.
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KEYWORD
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